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Ochre Bio

Many donor livers are too unhealthy or damaged to be transplanted and so go to waste, even though one in six patients die waiting for a new liver. The main reason for discarding a donor liver is that it contains too much fat. We rejuvenate these fatty donor livers by directly targeting over-active genes, making these livers transplantable.

We use recent breakthroughs in genomics to find and shut down over-active genes driving disease, and then go straight to testing our therapies in discarded donor livers that we keep alive on a machine. This approach makes us better, cheaper, and faster than traditional drug discovery.

Founded In



Hoxton II


London, UK

Invested In


Hoxton Partners

Rob Kniaz